27th April 2020

A paper published today in Scientific Reports documents the research underpinning Neuronostics’ technology.

The R&D team in Neuronostics are building on these findings, which will enable diagnostic and prognostic features currently hidden within the EEG to be made available to neurophysiologists and neurologists. These decision support tools will provide faster and more accurate diagnosis for people with suspected epilepsy, and provide them with greater certainty than at present.

Professor John Terry, senior author of the study from the University of Birmingham and co-founder of Neuronostics, said: “Almost 70% of recordings of electrical activity of the brain appear to be clinically normal. Our work adds to a growing body of evidence that demonstrates susceptibility to seizures can be revealed from these apparently normal electrical recordings.

“This will provide benefits to many people with suspected epilepsy, who cite uncertainty and delay as two critical issues with current approaches to epilepsy diagnosis. Previous work had established the potential of our methods with respect to generalised epilepsies, but this study includes a cohort with focal epilepsies alongside the generalised epilepsies, and broadens the potential of our tools to differentiate between these different classes of epilepsy.

“Neuronostics was created to take this research forward and ensure its use in clinic benefitting those suspected of having epilepsy. This could contribute to diagnosis being made more quickly and with greater accuracy than at present.”

The paper is open access, and is freely available to read and download.

Woldman, W., Schmidt, H., Abela, E. et al. Dynamic network properties of the interictal brain determine whether seizures appear focal or generalised. Sci Rep 10, 7043 (2020).

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